Senin, 31 Januari 2011

[U334.Ebook] PDF Ebook General Techniques of Cell Culture (Handbooks in Practical Animal Cell Biology), by Maureen A. Harrison, Ian F. Rae

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General Techniques of Cell Culture (Handbooks in Practical Animal Cell Biology), by Maureen A. Harrison, Ian F. Rae

General Techniques of Cell Culture (Handbooks in Practical Animal Cell Biology), by Maureen A. Harrison, Ian F. Rae



General Techniques of Cell Culture (Handbooks in Practical Animal Cell Biology), by Maureen A. Harrison, Ian F. Rae

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General Techniques of Cell Culture (Handbooks in Practical Animal Cell Biology), by Maureen A. Harrison, Ian F. Rae

Cell culture techniques are invaluable to the modern researcher but difficult to carry out successfully. As part of the series of Handbooks in Practical Animal Cell Biology, this volume offers a concise practical guide to the basic essentials of the technique. Researchers new to cell culture will find a clear explanation of the essential equipment of a tissue culture facility, including tissue culture media and sera. It describes methods for growing suspension and adhesion cultures, including how to store cells and prepare primary cultures from cells. For those already culturing cells, the handbook will act as a handy reference to the basic techniques. The essence of the book is to deal with the generalities of cell culture and to give a grasp of the basic concepts before involvement in more specialized work in the field. Ideal for anyone moving into tissue cell culture techniques or looking for a concise reference book.

  • Sales Rank: #2252483 in Books
  • Published on: 1997-10-13
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.98" h x .39" w x 5.98" l, .61 pounds
  • Binding: Paperback
  • 176 pages

Review
"...the sources used are authoritative, and the overall execution excellent. Anyone working with this type of cell culture would find this volume a highly valuable resource. The future volumes of this excellent series will be eagerly anticipated." Sara Abraham, Canadian Journal of Medical Laboratory Science

Most helpful customer reviews

20 of 20 people found the following review helpful.
From Book to Bench-Cell Culturing Made Easy
By palmorris brooks
Whether a first year college student or a seasoned researcher, General Techniques of Cell Culture is a must. GTCC simplifies the complicated world of cell culturing without insulting. The authors, Maureen A. Harrison and Ian F. Rae, make no assumptions about their readers, and take the task of explaining large amounts of scientific information in an organized and easy to read format. This handbook goes beyond general lab techniques and provides not only the "how-to", but also gives the developing lab the where at, as it rounds out each section with a directory of services and researchable references. By providing time honored techniques, General Techniques of Cell Culture also takes some of the trial and error out of propagating healthy cells in the lab. This alone should make the transition from book to bench less tedius and more productive.

0 of 0 people found the following review helpful.
good content but.....
By Autumn Girl
The content of this book is good, but come on, it is smaller than a typical novel - and not even printed/covered as nicely as a hard back novel - and it sells for $110.00 - buy the paperback it is actually printed and covered in higher quality at 1/3 the price.

0 of 0 people found the following review helpful.
Good basic techniques and explanations
By Cat Lady
Although outdated with regards to the equipment available, this book has good, easy-to-understand explanations of culturing cells and the principles and maintenance involved. Would definitely recommend it as a great reference for beginners.

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Sabtu, 29 Januari 2011

[X273.Ebook] Download Ebook Escrever melhor: guia para passar os textos a limpo (Portuguese Edition), by Arlete Salvador, Dad Squarisi

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� poss�vel transformar um texto comum numa escrita sedutora, gostosa de se ler? Em Escrever melhor: guia para passar os textos a limpo, Dad Squarisi e Arlete Salvador mostram como estudantes, jornalistas, advogados, executivos e outros profissionais que usam a escrita no dia-a-dia podem melhorar seu texto, tornando-o conciso, objetivo, claro e... sedutor. O livro aponta os defeitos mais comuns - em relat�rios, documentos, reportagens, disserta��es, teses e peti��es - e indica como escapar das ciladas da l�ngua portuguesa.

  • Sales Rank: #1977811 in eBooks
  • Published on: 2012-11-26
  • Released on: 2012-11-26
  • Format: Kindle eBook

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Selasa, 25 Januari 2011

[D987.Ebook] Download PDF International Logistics: The Management of International Trade Operations, by Pierre A. David

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International Logistics: The Management of International Trade Operations, by Pierre A. David

A full-color textbook covering all of the concepts of international logistics. This textbook is written from the perspective of the users, those managers who are actively exporting or importing goods or are otherwise involved in international trade operations. All of the relevant issues are thoroughly explained, including documentation, terms of payment, terms of trade (2010 Incoterms� rules), exchange rate exposure hedges, international insurance, Customs clearance, agency and distributorship sales contracts, packaging, transportation, and security issues.

  • Sales Rank: #42826 in Books
  • Brand: Brand: Cicero Books LLC
  • Published on: 2013-07-29
  • Original language: English
  • Number of items: 1
  • Dimensions: 10.80" h x 8.40" w x 1.50" l, .0 pounds
  • Binding: Paperback
  • 721 pages
Features
  • Used Book in Good Condition

About the Author
Pierre David is a Professor of Business Administration at Baldwin Wallace University, a liberal arts institution located in Berea, Ohio. His teaching interests are in marketing and operations management, particularly as these disciplines are applied to an international environment: his primary teaching focus are the courses in international logistics and international market research offered as part of the Baldwin Wallace International MBA program. His regular teaching schedule also includes courses in international marketing, market research, and operations management at the graduate and undergraduate levels. Based upon student recommendations, he has received the Bechberger Award for Excellence in Teaching. He earned a PhD from Kent State University, an MBA from the University of Pittsburgh, and an MBA from l'\'{E}cole de Hautes \'{E}tudes Commerciales du Nord in Lille, France, all of which were in marketing and operations management. Pierre has had the opportunity to conduct international logistics training sessions in the United States, France, Turkey, China and Brazil. He has lived in four different countries (Tunisia, Switzerland, France, and the United States) and visited a dozen more.

Most helpful customer reviews

3 of 3 people found the following review helpful.
David's book excels!
By Alexandre Winkler
The book covers all the essential topics regarding international logistics. As a matter of information, I read the brazilian version of the book and got surprised that such version was adapted to particular points as for brazilian practices. This is not very common concerning translated books whatsoever - a quality that differentiates David's book from other books. As a general rule, foreign books are verbatim translations of their original versions.

3 of 3 people found the following review helpful.
Five Stars
By Maria Gorbunova
A comprehensive reference book to start and to teach at the bachellor level.

2 of 2 people found the following review helpful.
Necessity for any Entrepreneur
By Waffles
I really love this book. Its easy on the eyes and keeps the reader engaged. I bought this book to learn about International trade for my classes and I'm glad I did. I has everything from the history of logistics, statistics, and in depth foundation of shipping.

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Kamis, 20 Januari 2011

[H552.Ebook] Download PDF Marriage Covenant, by Derek Prince

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Marriage Covenant, by Derek Prince

Is your marriage less than what you envisioned? Are you suffering in a bad marriage, but don't want to be the next divorce statistic?
If you find yourselves divided as a couple while you focus on who is at fault rather than what can be done – here is the answer!
In Marriage Covenant, Derek Prince unravels the principle of covenant and how we can build "a cord of three strands" that cannot be broken.
By following God's plan for marriage, you will build a relationship that faces difficulties, overcomes them, and emerges stronger than ever.
Discover a cherished love the most people only dream about.

  • Sales Rank: #387025 in Books
  • Brand: Lake Book
  • Published on: 2006-05-26
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.18" h x .47" w x 5.36" l, .40 pounds
  • Binding: Paperback
  • 176 pages

From the Back Cover
Is your marriage less than what you envisioned? Are you suffering in a bad marriage, but don't want to be the next divorce statistic?
If you find yourselves divided as a couple for days, even weeks, while the two of you focus on who is at fault rather than what can be done – here is the answer! Discover:
� God's original intent for marriage
� The "cord of three strands" principle
� Taking your marriage from bitterness to blissful
� What qualities to look for in a spouse
� Preventing and confronting conflict
� Making lovemaking a joy with true intimacy
� How to be irresistible to your spouse
By following God's plan for marriage, you will build a relationship that faces difficulties, overcomes them, and emerges stronger than ever.

About the Author
Internationally recognized as a Bible scholar and spiritual patriarch, Derek Prince (1915–2003) was educated as a scholar of classical languages at Eton College and Cambridge University in England, and later at Hebrew University in Israel. While serving with the British army in World War II, he began to study the Bible as a philosophical work and, as a result, experienced a life–changing encounter with Jesus Christ. Derek Prince taught and ministered on six continents for more than sixty years, imparting God's revealed truth, praying for the sick and afflicted, and sharing his prophetic insights into world events in the light of Scripture. He wrote over fifty books, which have been translated in over sixty languages and distributed worldwide. He pioneered teaching on such groundbreaking themes as generational curses, the biblical significance of Israel, and demonology. Derek Prince Ministries, with its international headquarters in Charlotte, North Carolina, carries on the good work that God began in and through him by distributing his teachings and by training missionaries, church leaders, and congregations through its worldwide network of offices.

Most helpful customer reviews

0 of 0 people found the following review helpful.
Five Stars
By Amazon Customer
Any couple that is getting married should defintely read this book.

0 of 0 people found the following review helpful.
Highly recommend.
By HE Lives
Definitely an eye opener and sound biblical teaching.

0 of 0 people found the following review helpful.
Five Stars
By Gerald Whitaker
good

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How We Learn: The Surprising Truth About When, Where, and Why It Happens, by Benedict Carey

In the tradition of The Power of Habit and Thinking, Fast and Slow comes a practical, playful, and endlessly fascinating guide to what we really know about learning and memory today—and how we can apply it to our own lives.

From an early age, it is drilled into our heads: Restlessness, distraction, and ignorance are the enemies of success. We’re told that learning is all self-discipline, that we must confine ourselves to designated study areas, turn off the music, and maintain a strict ritual if we want to ace that test, memorize that presentation, or nail that piano recital.

But what if almost everything we were told about learning is wrong?�And what if there was a way to achieve more with less effort?

In How We Learn, award-winning science reporter Benedict Carey sifts through decades of education research and landmark studies to uncover the truth about how our brains absorb and retain information. What he discovers is that, from the moment we are born, we are all learning quickly, efficiently, and automatically; but in our zeal to systematize the process we have ignored valuable, naturally enjoyable learning tools like forgetting, sleeping, and daydreaming. Is a dedicated desk in a quiet room really the best way to study? Can altering your routine improve your recall? Are there times when distraction is good? Is repetition necessary? Carey’s search for answers to these questions yields a wealth of strategies that make learning more a part of our everyday lives—and less of a chore.

By road testing many of the counterintuitive techniques described in this book, Carey shows how we can flex the neural muscles that make deep learning possible. Along the way he reveals why teachers should give final exams on the first day of class, why it’s wise to interleave subjects and concepts when learning any new skill, and when it’s smarter to stay up late prepping for that presentation than to rise early for one last cram session. And if this requires some suspension of disbelief, that’s because the research defies what we’ve been told, throughout our lives, about how best to learn.

The brain is not like a muscle, at least not in any straightforward sense. It is something else altogether, sensitive to mood, to timing, to circadian rhythms, as well as to location and environment. It doesn’t take orders well, to put it mildly. If the brain is a learning machine, then it is an eccentric one. In How We Learn, Benedict Carey�shows us how to exploit its quirks to our advantage.

Praise for How We Learn

“This book is a revelation. I feel as if I’ve owned a brain for fifty-four years and only now discovered the operating manual.”—Mary Roach, bestselling author of Stiff and Gulp

“A welcome rejoinder to the faddish notion that learning is all about the hours put in.”—The New York Times Book Review

“A valuable, entertaining tool for educators, students and parents.”—Shelf Awareness

“How We Learn is more than a new approach to learning; it is a guide to making the most out of life. Who wouldn’t be interested in that?”—Scientific American

“I know of no other source that pulls together so much of what we know about the science of memory and couples it with practical, practicable advice.”—Daniel T. Willingham, professor of psychology at the University of Virginia

  • Sales Rank: #143137 in Books
  • Published on: 2014-09-09
  • Released on: 2014-09-09
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.52" h x .83" w x 5.39" l, 1.25 pounds
  • Binding: Hardcover
  • 272 pages

Review
“This book is a revelation. I feel as if I’ve owned a brain for fifty-four years and only now discovered the operating manual. For two centuries, psychologists and neurologists have been quietly piecing together the mysteries of mind and memory as they relate to learning and knowing. Benedict Carey serves up their most fascinating, surprising, and valuable discoveries with clarity, wit, and heart. I wish I’d read this when I was seventeen.”—Mary Roach, bestselling author of�Stiff�and�Gulp

“How We Learn makes for a welcome rejoinder to the faddish notion that learning is all about the hours put in. Learners, [Benedict] Carey reminds us, are not automatons.”—The New York Times Book Review

“The insights of How We Learn apply to far more than just academic situations. Anyone looking to learn a musical instrument would benefit from understanding what frequency and type of practice is most effective. Even readers with little practical use for Carey’s information will likely find much of it fascinating, such as how intuition can be a teachable skill, or that giving practice exams at the very beginning of a semester improves grades. How We Learn is a valuable, entertaining tool for educators, students and parents.”—Shelf Awareness

“How We Learn is more than a new approach to learning; it is a guide to making the most out of life. Who wouldn’t be interested in that?”—Scientific American

“Whether you struggle to remember a client’s name, aspire to learn a new language, or are a student battling to prepare for the next test, this book is a must. I know of no other source that pulls together so much of what we know about the science of memory and couples it with practical, practicable advice.”—Daniel T. Willingham, professor of psychology at the University of Virginia and author of�Raising Readers in an Age of Distraction

“How We Learn is as fun to read as it is important, and as much about how to live as it is about how to learn. Benedict Carey’s skills as a writer, plus his willingness to mine his own history as a student, give the book a wonderful narrative quality that makes it all the more accessible—and all the more effective as a tutorial.”—Robert A. Bjork, Distinguished Research Professor, Department of Psychology, University of California, Los Angeles

“Fact #1: Your brain is a powerful and eccentric machine, capable of performing astonishing feats of memory and skill. Fact #2: Benedict Carey has written a book that will inspire and equip you to use your brain in a more effective way. Fact #3: You should use your brain—right now—to buy this book for yourself and for anyone who wants to learn faster and better.”—Daniel Coyle, bestselling author of The Talent Code

About the Author
Benedict Carey is an award-winning science reporter who has been at The New York Times since 2004, and one of the newspaper’s most emailed reporters. He graduated from the University of Colorado with a bachelor’s degree in math and from Northwestern University with a master’s in journalism, and has written about health and science for twenty-five years. He lives in New York City.

Excerpt. � Reprinted by permission. All rights reserved.
Chapter One

The Story Maker

The Biology of Memory

The science of learning is, at bottom, a study of the mental muscle doing the work—the living brain—and how it manages the streaming sights, sounds, and scents of daily life. That it does so at all is miracle enough. That it does so routinely is beyond extraordinary.

Think of the waves of information rushing in every waking moment, the hiss of the kettle, the flicker of movement in the hall, the twinge of back pain, the tang of smoke. Then add the demands of a typical layer of multitasking—say, preparing a meal while monitoring a preschooler, periodically returning work emails, and picking up the phone to catch up with a friend.

Insane.

The machine that can do all that at once is more than merely complex. It’s a cauldron of activity. It’s churning like a kicked beehive.

Consider several numbers. The average human brain contains 100 billion neurons, the cells that make up its gray matter. Most of these cells link to thousands of other neurons, forming a universe of intertwining networks that communicate in a ceaseless, silent electrical storm with a storage capacity, in digital terms, of a million gigabytes. That’s enough to hold three million TV shows. This biological machine hums along even when it’s “at rest,” staring blankly at the bird feeder or some island daydream, using about 90 percent of the energy it burns while doing a crossword puzzle. Parts of the brain are highly active during sleep, too.

The brain is a dark, mostly featureless planet, and it helps to have a map. A simple one will do, to start. The sketch below shows several areas that are central to learning: the entorhinal cortex, which acts as a kind of filter for incoming information; the hippocampus, where memory formation begins; and the neocortex, where conscious memories are stored once they’re flagged as keepers.

This diagram is more than a snapshot. It hints at how the brain operates. The brain has modules, specialized components that divide the labor. The entorhinal cortex does one thing, and the hippocampus does another. The right hemisphere performs different functions from the left one. There are dedicated sensory areas, too, processing what you see, hear, and feel. Each does its own job and together they generate a coherent whole, a continually updating record of past, present, and possible future.

In a way, the brain’s modules are like specialists in a movie production crew. The cinematographer is framing shots, zooming in tight, dropping back, stockpiling footage. The sound engineer is recording, fiddling with volume, filtering background noise. There are editors and writers, a graphics person, a prop stylist, a composer working to supply tone, feeling—the emotional content—as well as someone keeping the books, tracking invoices, the facts and figures. And there’s a director, deciding which pieces go where, braiding all these elements together to tell a story that holds up. Not just any story, of course, but the one that best explains the “material” pouring through the senses. The brain interprets scenes in the instants after they happen, inserting judgments, meaning, and context on the fly. It also reconstructs them later on—what exactly did the boss mean by that comment?—scrutinizing the original footage to see how and where it fits into the larger movie.

It’s a story of a life—our own private documentary—and the film “crew” serves as an animating metaphor for what’s happening behind the scenes. How a memory forms. How it’s retrieved. Why it seems to fade, change, or grow more lucid over time. And how we might manipulate each step, to make the details richer, more vivid, clearer.

Remember, the director of this documentary is not some film school graduate, or a Hollywood prince with an entourage. It’s you.

•••

Before wading into brain biology, I want to say a word about metaphors. They are imprecise, practically by definition. They obscure as much as they reveal. And they’re often self-serving, crafted to serve some pet purpose—in the way that the “chemical imbalance” theory of depression supports the use of antidepressant medication. (No one knows what causes depression or why the drugs have the effects they do.)

Fair enough, all around. Our film crew metaphor is a loose one, to be sure—but then so is scientists’ understanding of the biology of memory, to put it mildly. The best we can do is dramatize what matters most to learning, and the film crew does that just fine.

To see how, let’s track down a specific memory in our own brain.

Let’s make it an interesting one, too, not the capital of Ohio or a friend’s phone number or the name of the actor who played Frodo. No, let’s make it the first day of high school. Those tentative steps into the main hallway, the leering presence of the older kids, the gunmetal thump of slamming lockers. Everyone over age fourteen remembers some detail from that day, and usually an entire video clip.

That memory exists in the brain as a network of linked cells. Those cells activate—or “fire”—together, like a net of lights in a department store Christmas display. When the blue lights blink on, the image of a sleigh appears; when the reds come on, it’s a snowflake. In much the same way, our neural networks produce patterns that the brain reads as images, thoughts, and feelings.

The cells that link to form these networks are called neurons. A neuron is essentially a biological switch. It receives signals from one side and—when it “flips” or fires—sends a signal out the other, to the neurons to which it’s linked.

The neuron network that forms a specific memory is not a random collection. It includes many of the same cells that flared when a specific memory was first formed—when we first heard that gunmetal thump of lockers. It’s as if these cells are bound in collective witness of that experience. The connections between the cells, called synapses, thicken with repeated use, facilitating faster transmission of signals.

Intuitively, this makes some sense; many remembered experiences feel like mental reenactments. But not until 2008 did scientists capture memory formation and retrieval directly, in individual human brain cells. In an experiment, doctors at the University of California, Los Angeles, threaded filament-like electrodes deep into the brains of thirteen people with epilepsy who were awaiting surgery.

This is routine practice. Epilepsy is not well understood; the tiny hurricanes of electrical activity that cause seizures seem to come out of the blue. These squalls often originate in the same neighborhood of the brain for any one individual, yet the location varies from person to person. Surgeons can remove these small epicenters of activity but first they have to find them, by witnessing and recording a seizure. That’s what the electrodes are for, pinpointing location. And it takes time. Patients may lie in the hospital with electrode implants for days on end before a seizure strikes. The UCLA team took advantage of this waiting period to answer a fundamental question.

Each patient watched a series of five- to ten-second video clips of well-known shows like Seinfeld and The Simpsons, celebrities like Elvis, or familiar landmarks. After a short break, the researchers asked each person to freely recall as many of the videos as possible, calling them out as they came to mind. During the initial viewing of the videos, a computer had recorded the firing of about one hundred neurons. The firing pattern was different for each clip; some neurons fired furiously and others were quiet. When a patient later recalled one of the clips, say of Homer Simpson, the brain showed exactly the same pattern as it had originally, as if replaying the experience.

“It’s astounding to see this in a single trial; the phenomenon is strong, and we knew we were listening in the right place,” the senior author of the study, Itzhak Fried, a professor of neurosurgery at UCLA and Tel Aviv University, told me.

There the experiment ended, and it’s not clear what happened to the memory of those brief clips over time. If a person had seen hundreds of Simpsons episodes, then this five-second clip of Homer might not stand out for long. But it could. If some element of participating in the experiment was especially striking—for example, the sight of a man in a white coat fiddling with wires coming out of your exposed brain as Homer belly-laughed—then that memory could leap to mind easily, for life.

My first day of high school was in September 1974. I can still see the face of the teacher I approached in the hallway when the bell rang for the first class. I was lost, the hallway was swarmed, my head racing with the idea that I might be late, might miss something. I can still see streams of dusty morning light in that hallway, the ugly teal walls, an older kid at his locker, stashing a pack of Winstons. I swerved beside the teacher and said, “Excuse me” in a voice that was louder than I wanted. He stopped, looked down at my schedule: a kind face, wire-rimmed glasses, wispy red hair.

“You can follow me,” he said, with a half smile. “You’re in my class.”

Saved.

I have not thought about that for more than thirty-five years, and yet there it is. Not only does it come back but it does so in rich detail, and it keeps filling itself out the longer I inhabit the moment: here’s the sensation of my backpack slipping off my shoulder as I held out my schedule; now the hesitation in my step, not wanting to walk with a teacher. I trailed a few steps behind.

This kind of time travel is what scientists call episodic, or autobiographical memory, for obvious reasons. It has some of the same sensual texture as the original experience, the same narrative structure. Not so with the capital of Ohio, or a friend’s phone number: We don’t remember exactly when or where we learned those things. Those are what researchers call semantic memories, embedded not in narrative scenes but in a web of associations. The capital of Ohio, Columbus, may bring to mind images from a visit there, the face of a friend who moved to Ohio, or the grade school riddle, “What’s round on both sides and high in the middle?” This network is factual, not scenic. Yet it, too, “fills in” as the brain retrieves “Columbus” from memory.

In a universe full of wonders, this has to be on the short list: Some molecular bookmark keeps those neuron networks available for life and gives us nothing less than our history, our identity.

Scientists do not yet know how such a bookmark could work. It’s nothing like a digital link on a computer screen. Neural networks are continually in flux, and the one that formed back in 1974 is far different from the one I have now. I’ve lost some detail and color, and I have undoubtedly done a little editing in retrospect, maybe a lot.

It’s like writing about a terrifying summer camp adventure in eighth grade, the morning after it happened, and then writing about it again, six years later, in college. The second essay is much different. You have changed, so has your brain, and the biology of this change is shrouded in mystery and colored by personal experience. Still, the scene itself—the plot—is fundamentally intact, and researchers do have an idea of where that memory must live and why. It’s strangely reassuring, too. If that first day of high school feels like it’s right there on the top of your head, it’s a nice coincidence of language. Because, in a sense, that’s exactly where it is.

•••

For much of the twentieth century scientists believed that memories were diffuse, distributed through the areas of the brain that support thinking, like pulp in an orange. Any two neurons look more or less the same, for one thing; and they either fire or they don’t. No single brain area looked essential for memory formation.

Scientists had known since the nineteenth century that some skills, like language, are concentrated in specific brain regions. Yet those seemed to be exceptions. In the 1940s, the neuroscientist Karl Lashley showed that rats that learned to navigate a maze were largely unfazed when given surgical injuries in a variety of brain areas. If there was some single memory center, then at least one of those incisions should have caused severe deficits. Lashley concluded that virtually any area of the thinking brain was capable of supporting memory; if one area was injured, another could pick up the slack.

In the 1950s, however, this theory began to fall apart. Brain scientists began to discover, first, that developing nerve cells—baby neurons, so to speak—are coded to congregate in specific locations in the brain, as if preassigned a job. “You’re a visual cell, go to the back of the brain.” “You, over there, you’re a motor neuron, go straight to the motor area.” This discovery undermined the “interchangeable parts” hypothesis.

The knockout punch fell when an English psychologist named Brenda Milner met a Hartford, Connecticut, man named Henry Molaison. Molaison was a tinkerer and machine repairman who had trouble keeping a job because he suffered devastating seizures, as many as two or three a day, which came with little warning and often knocked him down, out cold. Life had become impossible to manage, a daily minefield. In 1953, at the age of twenty-seven, he arrived at the office of William Beecher Scoville, a neurosurgeon at Hartford Hospital, hoping for relief.

Molaison probably had a form of epilepsy, but he did not do well on antiseizure drugs, the only standard treatment available at the time. Scoville, a well-known and highly skilled surgeon, suspected that whatever their cause the seizures originated in the medial temporal lobes. Each of these lobes—there’s one in each hemisphere, mirroring one another, like the core of a split apple—contains a structure called the hippocampus, which was implicated in many seizure disorders.

Scoville decided that the best option was to surgically remove from Molaison’s brain two finger-shaped slivers of tissue, each including the hippocampus. It was a gamble; it was also an era when many doctors, Scoville prominent among them, considered brain surgery a promising treatment for a wide variety of mental disorders, including schizophrenia and severe depression. And sure enough, postop, Molaison had far fewer seizures.

He also lost his ability to form new memories.

Every time he had breakfast, every time he met a friend, every time he walked the dog in the park, it was as if he was doing so for the first time. He still had some memories from before the surgery, of his parents, his childhood home, of hikes in the woods as a kid. He had excellent short-term memory, the ability to keep a phone number or name in mind for thirty seconds or so by rehearsing it, and he could make small talk. He was as alert and sensitive as any other young man, despite his loss. Yet he could not hold a job and lived, more so than any mystic, in the moment.

Most helpful customer reviews

124 of 126 people found the following review helpful.
An enjoyable read, very effective!
By iWin
Benedict Carey's "How We Learn" is focused on the process of enhancing and exercising our memories in order to achieve positive results in memorization. He goes in depth in helping his readers enhance their memories through several techniques, in order to register, store and retrieve information. Most of us are not aware that our brains are capable of so much, but Benedict Carey makes the process look easy. Some of his techniques range from beginners techniques, to more advanced. I pretty much have the beginners techniques down pact; I would like to divulge into the more advanced techniques, as enhancing my memory has become a number one priority in my life.

Repetition, according to Benedict, is a vital part in helping us to enhance the memory. We must train our brains, in a way, so that certain things we may forget become more and more routine to us. For example, I sometimes forget to lock all the doors in my house before going to sleep. If I am aware of this and practice locking the doors each and every night, soon enough it will become routine to me and I'll no longer forget to do it.

I read this book, in conjunction with Greg Frosts book, "Maximizing Brain Control : Unleash The Genius In You", and I'm starting to feel more confident and knowledgeable in learning about the human brain and how to store and retrieve information. Both are excellent resources and combined, can truly work wonders for you if you take them serious and truly want to enhance your brain capacity.

Good Habits is a key technique both books teach. If you can associate certain things with something you are more familiar with, you are more likely to start remembering as time goes on. Problem Solving is a third technique in which Benedict explains. If you can train your brain to solve the problem that need to be completed, we also learn the upside of distraction.

He also provides dietary advice that can help to improve our memory. Most of us would not think or believe that sleep actually plays a vital role in our brain function and memorization, but it does. Something as simple as making small changes in our lifestyle can actually enhance our memories.

197 of 202 people found the following review helpful.
Deserves a Wide Reading
By Evelyn Uyemura
I keep up fairly well with research in the field of psychology and learning in particular, so much of this information was not entirely new and surprising to me, but Benedict Carey does a great job of pulling a lot of different research together and presenting it a practical way. This is more a guide to what is known than a self-help book, but it will definitely be of use both to teachers and students who want to understand how to study more effectively.

A couple of take-aways--half-forgetting and then re-learning, especially by trying to remember, make the thing you are trying to learn really stick. So as a teacher, when I start class on Monday and ask students to recall what it was we were working on last Friday, that is not just review--that is learning. It would be best, I suppose, if instead of asking the whole class and letting one or two students do the hard work, I had everyone try their best to write down what the remember about passive voice or the subjunctive.

That brings up another great point that he makes--that testing, quizzing, and self-testing are highly effective ways not of evaluating but of actually learning. This helps to overcome what he calls the Fluency Illusion, and what I have long called the "smile-and-nod" level of understanding. IN other words, when the teacher is doing math problems on the board and you are watching, you understand--you smile and nod and think, ok, yeah, sure, I get it. It is only when the tables are turned and the teacher says, Ok, now you try it, that the gaps in understanding are revealed.

So if you are studying for a test on state capitals, let's say, and you see Georgia: Atlanta, you think right, sure. But it's not until someone says Georgia and you can say Atlanta that you actually know it. And each time you test yourself, or have someone else test you, you are retrieving and then re-storing that memory, making it more salient. I would go so far as to suggest that one difference between middle-class kids and poor kids in school is that middle-class parents often quiz their kids on their school-work. "Let's go over those state capitals together," and less-educated parents probably don't. That could be enough to make a big difference, since this is such a powerful learning tool.

He also reports on interesting work on how location and distraction can help rather than hurt our learning--studying in a variety of places, with varying amounts of distraction can help us remember more. And spaced practice works better than intense practice. IN other words, if you have one hour to learn the capitals of all the countries in Europe, or the parts of the hand, it would be better to do 3 20-minute sessions, especially if you sleep between at least two of the sessions, than to do all 60 minutes at once. And what about cramming? We don't really need research to tell us this, but yes, it works if your only goal is to pass the test, but if you actually want to learn the material, it is worthless. You forget it as fast as you "learned" it.

One great point to this book is that he covers widely diverse fields of study--from physical skills like a golf swing or a tennis serve, to complex skills like flying a plane, to rote memorization, such as vocabulary or state capitals., to comprehension of difficult concepts like economics or physics. Many of the techniques he describes apply across the board, and others are more particular to certain types of learning. For example, for physical performance (a piano recital or a baseball tryout, you do better if you sleep in a bit, getting plenty of the kind of sleep that occurs towards morning. For memory like a vocabulary test, it's better to get plenty of the early-stage sleep, so go to bed on time and get up early in the morning to review. Your brain does a lot of memory consolidation while you sleep, and specific types in specific stages.

One point that he doesn't directly address but that I am familiar with the research on is whether it's better to memorize large things as a whole or in chunks. For example, if you are an actor, or you want to memorize a long poem or speech, should you work on the first sentence, and then the second sentence, and so on, or should you go through the whole thing each time. The answer is that you should do it whole--it will feel like you're not getting anywhere at first, but suddenly, the whole thing will be in there This fits with what he says about inter-leaving---practicing a variety of different things in each session rather than chunking it all together--master skill A before moving on to skill B. No, it's better to do some A, some B, and some C, even though it will feel like you aren't making progress at first.

I recommend this book to every teacher of any subject, and to anyone who is a student at any level, and to parents, who worry that their kids are too distracted and unfocused in the way they study--turns out that distraction and lack of focus can serve you well!

92 of 97 people found the following review helpful.
How to be a better learner seems to be a big trend in recent ...
By B.L.
There's plenty of information here to work with. How to be a better learner seems to be a big trend in recent books. In the past couple of months I've read Fluent Forever (about language learning) and A Mind For Numbers (about being a good student, particularly in math and science) and they've all been released at the same time. They're also all, I'm very happy to say, strongly grounded in real research, rather than just making up some interesting-sounding notions about what might work (I have certainly seen books that did that...)

I would have to say that someone who wants to be a great student ASAP is probably better off reading A Mind For Numbers first. That book takes you by the hand and leads you through the ideas about what you need to DO a lot more specifically. It makes very frequent references to research, but it's plainly written with the intention of being a guide for people who are taking and really need to hone in on exactly what to do NOW, because there are tests coming up. It leads you through the material by the hand, pretty much, asking you questions and reminding you to stop and think about what you've read. It also has a (free) online MOOC through Coursera to go with it that covers/reinforces the same material.

Fluent Forever, in its effort to teach people how to learn languages, makes use of some of the same research, but shapes it to its topic. It offers a sort of general idea of how you should proceed, but the emphasis is on giving you a basic plan and just enough understanding of the research so that you can make good decisions about how to move forward with it.

I feel like How We Learn is a little farther down the spectrum in that same direction. Most of its emphasis is on teaching you the research (some of which is the same research cited by the other two), with an assumption that you'll be able to make reasonable decisions about how to put it into practice. So he goes over exactly why it is NOT a good idea to learn a new math trick by doing 50 problems in a row that use that trick. He touches on how it can be put into practice, but it isn't something he dwells on. This vs A Mind for Numbers is sort of like... one being a professor who teaches key points but assumes that the students are capable of drawing some reasonable conclusions on their own, and the other being a professor who strives to touch on every single possible issue that might be of importance. It's a very different style.

For someone who's actually writing a paper on learning or something of that nature, I suspect this will be more valuable. For someone who is actively taking classes or trying to learn a language, I'd say read either A Mind for Numbers or Fluent Forever first, because they'll get you going on making progress faster. Then, it certainly wouldn't hurt to come back to review some of the concepts and generally deepen your understanding overall by reading How We Learn. (If you're not taking classes and you just love teaching yourself new things, you might want to skip A Mind for Numbers. It puts a lot of emphasis on things like dealing with procrastination, which is very valuable, but not really a core issue if you're learning for pleasure and there aren't really any deadlines to speak of.)

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Sabtu, 15 Januari 2011

[I697.Ebook] Download Business Writing: What Works, What Won't, by Wilma Davidson

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Business Writing: What Works, What Won't, by Wilma Davidson

A thorough, accessible, and results-oriented guidebook intended for today's business environment, Business Writing: What Works, What Won't offers the first and last word on writing memos, business letters, reports, and all other kinds of business documents. Wilma Davidson, a veteran corporate writing coach whose clients have included M&M Mars, Johnson & Johnson, Anheuser-Busch, and several other Fortune 500 companies, uses clear and memorable examples, charts, cartoons, and anecdotes to convey exactly what succeeds--and what fails--in written business communication.

This new edition of Business Writing has been fully revised and updated to cover e-mail, Palm Pilots, and the latest in word processor technology. It will be an indispensable reference for all students of business and management--a book that answers questions about style, provides guidance in matters of grammar, and reveals countless insights about writing with precision, confidence, humor, and eye-catching effectiveness.

  • Sales Rank: #111588 in Books
  • Published on: 2001-05
  • Released on: 1994-08-15
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.05" h x .88" w x 6.96" l, 1.10 pounds
  • Binding: Paperback
  • 320 pages

From Library Journal
Business writing manuals tend to fall into two traps. One is dwelling on how much business people hate to write because of bad teachers in school (no one wants to admit that writing takes thinking). The other is inconsistency in tone-trying to use everyday business language but lapsing into quoting Shakespeare in Latin. This book avoids both traps. It has a good format for use in seminars and classes: Chapters are short and contain exercises and examples, humor, and illustrations to make their points clear and memorable. This book suggests some useful activities that don't often appear in similar manuals, such as clustering and writing dialog to get started, and wisely emphasizes getting the first draft done before doing any editing. Davidson is a 15-year veteran of teaching writing seminars in the corporate world for such companies as AT&T and Johnson & Johnson. Her manual is appropriate for public, academic, and corporate libraries.
Nancy Shires, East Carolina Univ., Greenville, N.C.
Copyright 1994 Reed Business Information, Inc.

From the Back Cover
Do your business memos get the results you want? Do you panic when it's time to write the year-end sales report, or that deal-clinching letter to a potential client? If so, you're not alone. Like you, many people who write on the job feel unsure about their skills, and wish there were simple guidelines for getting started and expressing themselves in winning ways. This practical, fun, confidence-boosting guide offers exactly those guidelines. Author Wilma Davidson shares her fifteen years of experience as a corporate writing coach, delivering the essential information, motivation, and inspiration needed to write more effectively on the job. Using dozens of sample letters, memos, and other real-office documents, plus engaging exercises and copious illustrations, Davidson covers every aspect of business writing, from conquering writer's block, to revising first drafts, to finessing the finer points of structure, argument, and style.

About the Author

Wilma Davidson, Ed. D., is a writing and presentation-skills coach. Her clients include corporations throughout the Fortune 500. She lives in East Greenwich, Rhode Island, and Longboat Key, Florida.

Most helpful customer reviews

2 of 2 people found the following review helpful.
Business Writers: It's a Keeper!
By M. Petras
For me, Business Writing: What Works, What Won't is a highlighted keeper. As a Professional Writing major, I need to know how to write results-oriented business documents and this book teaches "how"--- with a flair.

Taught are ways to get messages across in a professional and sincere tone. Dr. Davidson gives us permission to replace worn-out clich�s with sincere words. A "monkey see, monkey write" society is the easy way, but not the most actionable way. As Dr. Davidson suggests in the book, a supportive work climate is a more productive work climate. This is a message that is needed in today's stress-filled, power-hungry workplace. We can whistle while we work, and we can get things done...effectively. Not only does this book offer ideas on creating a sincere, authentic tone, there are also ways to help business writers become concise, complete and clear. We can achieve this through our writing and in the visual presentations or our documents. For those of us with a creative bone and a bit of computer proficiency ---providing "eye candy" makes business writing fun.Other text highlights include:

� Most frequently misspelled words - p 191 is a favorite carton caption

� Forming plural words - love the poem on p 213

� Getting rid of sentence clutter/"unsmothering" words - and the fun captions on pages 105-07

This book is a keeper, too, because it's different from other business books out there - it's full of cartoons and humorous examples. Business Writing: What Works, What Won't doesn't only tell, it shows.

10 of 10 people found the following review helpful.
The Book Does Work
By Glenn Gallagher
Business Writing: What Works, What Won't is a business writing book that indeed does work very well. The author gets right to the point and gives just the right amount of information on most business writing aspects, with a terrific section on e-mail and letters. She uses humor throughout the guide, making an otherwise dry subject more entertaining. More importantly, the book is full of useful examples that illustrate the rule, technique, or principle discussed. For example, she doesn't just urge the reader to use the active voice, she includes almost a dozen examples of the proper way to use the active voice (and avoid the passive voice). Highly recommended.

1 of 3 people found the following review helpful.
Great buy
By Vermonter16
This is actually one of the best business related books I have ever read because of how helpful and straight-forward the content is. I had Davidson as my professor and the way the book helps you to overcome any issues with writing for business is the best. I have recommended it to many friends too! This was a great price for an excellent buy! Definitely a keeper!

However, I was not completely satisfied with this product considering what I received was not what I ordered! It was a completely different edition than what was discussed in the comments and such on the product. The book did come very quickly and I was happy about that but I had to purchase another book because this was not the correct book I purchased online from this buyer. So just watch that Amazon sends you the correct edition!

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Kamis, 13 Januari 2011

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Owner name written on first end page. Shelf wear with small nick to board edge. There are writing/highlighting marks in the book. Most of the Pages are clean and binding is tight.

  • Sales Rank: #7413963 in Books
  • Published on: 1968
  • Binding: Hardcover

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Rabu, 12 Januari 2011

[H703.Ebook] Free Ebook Health Economics: Theories, Insights, and Industry Studies, by Rexford E. Santerre, Stephen P. Nuen

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  • Sales Rank: #1580412 in Books
  • Published on: 2006
  • Format: International Edition
  • Original language: English
  • Binding: Paperback
  • 608 pages

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